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KMID : 1094020150320020212
Journal of Veterinary Clinics
2015 Volume.32 No. 2 p.212 ~ p.214
Head Tilt Associated with Encephalitozoonosis in Four Pet Rabbits
Shin Jin-Cheol

Song Kun-Ho
Kim Sang-Hun
Kim Suk
Abstract
Encephalitoozoon cuniculi is an obligate intracellular microsporidian parasite commonly found in rabbits,causing encephalitozoonosis. This organism can also infect a wide range of hosts including humans, which is knownto cause opportunistic infections in immunocompromised individuals. In this case, four rabbits presented with headtilt and nystagmus were diagnosed for E. cuniculi infection using ELISA. The rabbits were treated with fenbendazolefor 4 weeks and therapeutic success was evaluated by assessing the neurological symptoms. Three out of 4 rabbitsshowed improved health condition 3 to 5 days after treatment, but one rabbit showed persistent anorexia and headtilt after treatment and then died after 10 days. This report is the first to investigate the therapeutic response offenbendazole for rabbit encephalitozoonosis in Korea, and suggests that pet rabbits may serve as potential E. cuniculireservoirs for both pet animals and humans.
KEYWORD
Encephalitozoon cuniculi, fenbendazole, rabbit
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